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医学 Peek 材料 PEEK-OPTIMA Polymer Brochure
Performance Purity Flexibility EndurancePerformanceA Winning FormulaPEEK-OPTIMA is a polyaromatic semicrystalline thermoplastic based on the basic formula (-C6H
4-O-C6H4-O-C6H4-CO-)n and is known generically as polyetheretherketone.Total HipPlate and PinsLigament Fixation WashersSpinal CagesPulmonary Artery BandQuality Assured, Every TimeIn compliance with ISO 9000 and ISO 13485PEEK-OPTIMA polymer from Invibio is a high performance biomaterial providing advanced solutions for implant manufacturers. Formulated to meet the most exacting in-vivo criteria, PEEK-OPTIMA is biocompatible, safe and stable.Manufacturers of cardiovascular, dental, neurological and orthopaedic implants choose PEEK-OPTIMA for its:
Excellent mechanical performance
High wear resistance
Ability to be repeatedly sterilized without impairing performance
Biocompatibility
Drug and Device Master Files lodged with the FDA Invibio offers a ‘no-change’ agreement for the assured long-term supply of PEEK-OPTIMA. This guarantees its specification and production methods over an agreed period of time.standards, Invibio embraces all the principles of Good Manufacturing Practice in relation to the manufacture of PEEK-OPTIMA unfilled granules, compounds and stock shapes. Enhanced quality control procedures and standards ensure a tight product specification for PEEK-OPTIMA including:
Complete batch and raw materials traceability
Accredited independent testing laboratory
Packaging in double lined, tamper-evident drums suitable for clean-room production.PEEK-OPTIMA Powder, Pellets, Rods and FilmPurityThe Decision is SimplePEEK-OPTIMA is an inherently pure, inert material. Extensive biocompatibility testing demonstrated no evidence of cytotoxicity, systemic toxicity, irritation or any macroscopic reaction response. Furthermore, very low levels of residual and extractable metal ions minimize the potential risk of allergic reactions commonly associated with nickel and other metal ions.PEEK-OPTIMA Biocompatibility Tests Genotoxicity ISO 10993-3
Hemolysis (Extract) ISO 10993-4
Cytotoxicity ISO 10993-5
Biostability: Local Effects of Implantation ISO 10993-6
Sensitization ISO 10993-10
Pyrogenicity ISO 10993-11
Chemical Analysis ISO 10993-18
USP Plastic Class VI Systemic Toxicity Study
USP Plastic Class VI Intracutaneous Toxicity StudyTried and TestedTest material implanted in paravertebral muscle for one year caused virtually no response-mild fibrosis, or in some cases a light fibrous capsule. There was no muscle degeneration, nor necrosis, or any other significant change.FibroblastMyocyteZone of ImplantationDMF and MAF files containing the results of these tests have been lodged with the FDA.Unlimited Design SolutionsThe PEEK-OPTIMA family, comprising three grades - standard viscosity, medium viscosity and low viscosity - is available in granular form for injection molding and/or extrusion. PEEK-OPTIMA can be processed by:
injection molding
extrusion (e.g. rod, tube, plate, monofilament and film)
compression molding Stock shapes are produced in a broad range of diameters for machined components.FlexibilityIt’s in the MixPEEK-OPTIMA compounds can be formulated using a variety of additives including carbon fiber, barium sulphate and glass fiber to satisfy a complete spectrum of application-specific requirements.Alumina PEEK-OPTIMA Composite Cobolt chromium 316 Stainless Titanium 6Al-4V 30% CF-PEEK-OPTIMA Human Femur 30% Glass PEEK-OPTIMA 20% BaSO4 PEEK-OPTIMA PEEK-OPTIMA 0 20 40 60 80 100 120 140 160Glass Fiber for Property EnhancementGlass fibers may be compounded with PEEK-OPTIMA polymer to enhance mechanical properties without substantially changing the color of the base material.Barium Sulphate for RadiopacityPEEK-OPTIMA polymer is naturally radiolucent. Adding barium sulphate at varying concentrations, as shown, allows the optical density of devices to be tailored from mild to strong radiopacity.Flexural Modulus (GPa)No filler4%6%20%Carbon Fiber for Added StrengthThe compounding of PEEK-OPTIMA with short carbon fibers, allows the strength of natural unfilled polymer to be increased significantly to address higher stress demanding applications.CompositesIn certain applications for which superior mechanical properties are required, PEEK-OPTIMA may be used as the matrix polymer in combination with continuous carbon fibers to form reinforced composite materials.EnduranceResilient and EnduringNatural, unfilled PEEK-OPTIMA is characterized by its high strength, extreme resistance to hydrolysis and resistance to the effects of ionizing radiation. Therefore, PEEK-OPTIMA can be repeatedly sterilized using conventional gamma irradiation, steam and ethylene oxide without significant deterioration of mechanical properties.Steam SterilizationThe chemical structure of PEEK-OPTIMA ensures extreme stability against hydrolysis, even at elevated temperatures. PEEK-OPTIMA can be steam sterilized repeatedly without reduction or deterioration in mechanical properties.Gamma SterilizationThe resilient chemical structure of PEEK-OPTIMA makes it very tolerant to gamma irradiation. However, gamma irradiation of other polymeric materials induces cross-linking and/or chain scission leading to weakening and embrittlement as shown below.The Oxidative Gamma Dose at Which a Slight Deterioration in Flexural Properties OccursEtO SterilizationEtO residues are within the limits specified in ISO 10993-7, even following three repeated sterilization cycles. 106 1054 3101 0PEEK-OPTIMA Silicone PolyimidePSUPCAcetalPTFEFor further information please visit our website at
or call us toll free at 866-INVIBIO or +44 (0).Invibio provides biomaterial solutions for the implantable medical device market. Headquartered in the UK with offices in the USA and Europe it is the sole world-wide manufacturer and distributor of PEEK-OPTIMA polymer, an advanced biomaterial suitable for long term implantation. The data provided is for evaluative purposes only. Actual PEEK-OPTIMA material specifications must be agreed to by Invibio and customer.Invibio Ltd. Technology Centre, Hillhouse International Thornton Cleveleys, Lancashire FY5 4QD United Kingdom Tel: +44 (0)
FAX: +44 (0)
Invibio Inc. 300 Conshohocken State Road West Conshohocken, PA USA 866-INVIBIO (468 4246) Tel: +484 342 6004 FAX: +484 342 6005 Invibio Ltd. Metropolis Tower, Unit 1, 12th Floor 10 Metropolis Drive Hunghom, Kowloon, Hong Kong Tel: +852
The BAK, BAK/C, Proximity, BP, BP/Lordotic, BAK Vista, and Vista Lordotic implants and the methods and instrumentation for implanting the same and utilized in the POLAr System are licensed under and protected by one or more of the following: U.S. Patents 5,015,247, 5,484,437, 5,741,253, 6,096,038, 6,080,155, 6,264,656 and 6,270,498 and related international patents issued to GARY KARLIN MICHELSON, M.D.; Centerpulse Spine-Tech Inc. U.S. Patents 5,489,308, 5,609,636 and 5,658,337 issued to GEORGE W. BAGBY, STEPHEN D. KUSLICH, and pending U.S. and international patent applications. Disclaimer The information contained in this brochure is believed to be an accurate description of the typical characteristics and/or uses of Invibio product(s). However, it is your ultimate responsibility to determine the performance, efficacy and safety of using Invibio product(s) for a specific application. Suggestions of uses should not be taken as inducements to infringe any particular patent or as a representation that the product is suitable for such uses. Invibio‘s sole warranty is that its product(s) meet its then current published specifications. Invibio specifically disclaims any other express or implied warranty, including the warranties of merchantability, non-infringement, and of fitness for a particular use or purpose. Invibio shall not be liable for any direct, indirect, incidental, special, or consequential damages, in contract, tort, or otherwise, arising out of the use of its product(s) or in connection with the information contained herein. The information and data contained herein are based on information believed reliable. Mention of a product in this documentation is not a guarantee of availability. Invibio reserves the right to modify products, specifications and/or packaging, as part of a continuous program of product development. Copyright
2004 Invibio Ltd. Invibio and the Invibio logo are registered trademarks of Invibio Ltd. PEEK-OPTIMA is a registered trademark of Invibio Ltd. Biomaterial Solutions is a trademark of Invibio Ltd.GOLD MEDALPO-ENG-B-01(12/01.03)
PEEK材料_机械/仪表_工程科技_专业资料。一、性能简介: 性能简介: 南京首塑特种工程塑料制品有限公司(原南京元邦工程塑料有限公司)模压加工聚醚醚酮(PEEK)管材、 棒...peek种类_材料科学_工程科技_专业资料。1、PEEK-1000 (褐灰色) PEEK-1000 使用纯的聚醚醚酮树脂为原料制造,在所有 PEEK 级别中韧性 最好,抗冲击最佳。 PEEK-...PEEK的材料性能_能源/化工_工程科技_专业资料。PEEK的简介与材料性能 PEEK (聚醚醚酮)材料的连续使用温度极高(大约 260 度),还具有极高的刚度和硬度,以及 聚醚...印刷电路板新型绝缘体材料PEEK_电子/电路_工程科技_专业资料。特点:液体涂覆,容易...新型绝缘体材料 ---紫外光交联的聚醚醚酮(PEEK)聚醚醚酮(polyetheretherketone,...PEEK 材料椎弓根内固定与椎间融合修复腰椎管狭窄症:植骨融合率随访评价 www.CRTER.org 1.3 材料 PEEK棒椎弓根内固定系统:由上海鑫舟医疗器械 的骨粒植入椎体...PEEK PPSU材料比较_能源/化工_工程科技_专业资料 暂无评价|0人阅读|0次下载|举报文档 PEEK PPSU材料比较_能源/化工_工程科技_专业资料。Unist SI 颜色 拉伸强度 ...有研究人员研究了成型工艺对玻璃纤维增强聚醚醚酮(GF/PEEK)复合材料 性能的影响...Journal of Applied Polymer Science, ): 3 379-3 387 [17] J...opolymer 丙烯晴一丙烯酸脂一苯乙烯共聚物 ABS ...(see CPE) 氯化聚乙烯 PEEK Polyether ether ketone...2014教师资格材料分析辅... 2014小学教师资格考试《...PEEK 不仅具有质量轻、无毒、耐腐蚀等优点,还是目前与人体骨骼 最接近的材料,可与肌体有机结合,所以用 PEEK 树脂代替金属制造人体骨骼是其在医疗领域的又一重要 ...PEEK是什么材料_机械/仪表_工程科技_专业资料。PEEK是什么材料,聚醚醚酮(PEEK)树脂PEEK 是什么材料 聚醚醚酮(PEEK)树脂是一种性能优异的特种工程塑料, 与其他特种...
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Zhang Lei Hillhouse: by the $ venture mentor to three thousand but take a cup of water
The college entrance exam, undergraduate, master, under the
tutelage of Yale's investment Godfather David Shi Wensen (David F.
Swensen), with a mentor to provide $ of venture investment
career, start. 2005, start at the beginning, he investedAt that
time, the market value of less than $ Tencent, now
Tencent worth more than $, he still holds a Tencent
stock. Jingdong shares, earnings over 40 times. He is,(Hillhouse Capital) founder.
Zhang Lei resume glittering, fortune and enviable ability. He
invested enterprises in their respective industries are Tencent
count as one of the very best, such as,Jingdong,
where to go, Lan Yueliang, the U.S. group, all information, taxi
drops etc. (schedule). At the end of 2014, Hillhouse capital
management funds of more than $. Zhang Lei is in
yuan of wealth among the "2015 new wealth of the 500
richest", ranked 279th.
Do long term partner enterprises
Hillhouse capital is used in Changqing Fund (Evergreen Fund)
model, is don't have to worry about the exit pressure, after the
listing of the company, as long as the prospects for the
development of business, the fund may have for a long time. To
realize this model, there are two factors: one is the investment
company's business philosophy and foundation, take a long-term
view, pattern o two is the investor (LP) in
the short term there is no exit requirements, the fund manager (GP)
can be carried out according to their own long-term investment
philosophy.
Long term investment of LP is high, LP needs to trust GP.
Hillhouse capital entrusted with the management of funds mainly
from the long-term vision of global institutional investors,
including university endowment funds, charitable funds, sovereign
wealth funds, pension funds and fund family etc.. When the capital
is a long-term sometimes, GP have to spend time thinking about what
conditions is the long-term prospects of the business model, what
kind of business is held for 30 years.
The reason why Zhang Lei can get these overseas long-term
capital favor, not only by the unique investment perspective, its
experience is closely linked. He studied at Yale University Fund
chief investment officer David Swenson, firm executor is Buffett
long held ideas. Shi Wensen led the "Yale model" to become the
godfather of institutional investors. Yale model beyond simple
investments in stocks and bonds, replace sb. is PE, real estate
investment and hedge funds. PE has become the core of "Yale model"
portfolio, and get as many funds. BeforeThe
investment management company chairman Barton Biggs said: "the
world's only two investors really great, they are Swenson and
Hillhouse capital at the beginning of the establishment of a
$ start-up capital, is from the Yale University endowment
fund, then the history of Vince adding $ to their favorite,
to help him carry out his own business in china. Experience is
crucial to Zhang Lei in Yale University study. This laid the
foundation for his experience as the investor's occupation career,
but also its investment philosophy formation period.
Zhang Lei was born in 1972, from Henan Zhumadian an ordinary
family, father is the local foreign trade bureau cadres. He went to
Zhumadian in the first liberal arts achievements in Renmin
University of China majoring in international finance. In 1998 he
went to study at Yale University American, obtained MBA from the
Yale University and a master's degree in international relations.
Zhang Lei studied at Yale University, in order to earn tuition,
once in the history of Vincent under the leadership of the Yale
University investment office, this experience let him exposed to
the history of Vincent investment ideas and skills, to lay the
foundation for its investment career.
After graduating from Zhang Lei in the global emerging market
investment fund over a period of time, is mainly responsible for
South Africa, Southeast Asia and China investment. Since its
Chinese also served as the chief representative of the New York
stock exchange first, and created the New York stock exchange in
Hongkong and Beijing office. In 2005, Zhang Lei founded Hillhouse
capital group.
In Zhang Lei's view, Svenson teaches the most important thing is
to give him their own beliefs like religious belief in general, do
not forget the beginning of the heart, the party must always. Zhang
Lei's faith, is long term business partner. A Yale University
endowment fund support, Zhang Lei's business to start, and
gradually get more long-term fund support. In order to return to
Yale, at the beginning of 2010, Zhang Lei donated $8888888 to his
alma mater, a Yale graduates the largest single personal donation
Weak water three thousand, but
take a scoop
"Water three thousand, but take a scoop" is Zhang Lei's
investment philosophy, is intended to alert people in life will
encounter a lot of good things, but as long as the heart of a good
grasp of one of them is enough. For Zhang Lei and Hillhouse
capital, is spotted the company and the business model will be
under the heavy note.
"With a great view of the pattern of firm practitioners", is
Zhang Lei's investment. He also said frankly, very few people and
companies have this pattern and execution, the company can push the
vision to the high altitude. In order to find such companies and
entrepreneurs, Hillhouse capital is used in the research of
tactics, through the study found that which model is the most
promising. If you can find this company in two markets, will buy
stocks long-term holders, if there is no such company, Hillhouse
capital looking for fit with the business model of entrepreneurs,
not their own hatching.
In the process of investment, the biggest risk is the candidate,
Zhang Lei's most important concern is to find the most suitable
entrepreneurs. This person is to have a long-term vision, pattern
view, want to do great things, execution, but also have a very deep
and sensitive to change the nature of things, and focus on a small
profit, playing a zero sum game people will be excluded from the
capital. He also said frankly, most people are in a certain period
of time or a very good, some people can through the communication
with the outside self.
Go where the founder Luo Qiuping Zhuang Chenchao and founder of
the blue moon are Zhang Lei's investment object. In the eyes of
Zhang Lei, the two are to do great things, long-term vision, to do
a Chinese largest travel search platform, the other one to defeat
transnational enterprise, become the leading cosmetic China. They
all have pattern view. Zhuang Chenchao is young but has
participated in entrepreneurship, has a strong learning ability and
the ability of insight, to control the shares sold to Baidu in
critical period, enjoy huge traffic brought by Baidu. Luo Qiuping
could have a very comfortable life, but he is willing to give up
the content with one hundred million or two hundred million yuan a
year profits of the company, the company at the loss of one or two
years ago, in order to open up a new world of the future.
Find the right person is just the first step, dare to achieve
the desired effect under the heavy note. In the case of capital
investment, the most is indulge in elaborating on the story of Liu
Qiangdong and Zhang Lei. At that time, the asset light model has
been in the field of electronic businessTo achieve
the ultimate, Zhang Lei after a study found that heavy assets,
similar to the integration of the supply chain model of UPS still
have a chance, he is also looking for the field of heavy assets of
the company. At that time many business entrepreneurs have to rely
on asset light model, only Liu Qiangdong was honest enough to tell
him to do the heavy assets. Two people fit in easily with.
Initially, Liu Qiangdong wanted to find Zhang Lei raised
$, but Zhang Lei told him a book, "this business without
money is not OK, or not to vote, to vote for us $ of
investment," he said in public. Finally, this round of investment
of $, $ from the capital, the remaining few from
other investors, capital shares accounted for 20.37%.
"We do this business business, I think there are one million
ways to let you die very badly, so we will lose $, the
fund lost two or three points, for me it is not worth mentioning,
but we want to bet their most trusted." Zhang Lei said.
Of course, this business not only let Zhang Lei lose money, but
earn pours. Data shows, in 2014 May, Jingdong listed, Hillhouse
capital holds
shares of Jingdong. By the end of 2014,
Hillhouse capital holdings to
shares. In order to
Hillhouse capital $ to get
shares to calculate,
Zhang Lei got Jingdong shares the cost price of about $0.825 per
share. In Jingdong Mall (JD.NSDQ) April 17, 2015 closing price of
$33.19 / share calculation, Hillhouse capital gains staggering 40
times, the book profit of nearly $.
In addition to the "weak water three thousand, but take a
scoop," Zhang Lei's investment philosophy and the "taolibuyan
xiazichengqi," refers to, as long as do the right thing, not
everywhere propaganda, good entrepreneurs will find them. "Keep is
odd" is his investment philosophy. The concept of inheritance from
history "is reflected in the" Vincent, investment managers
character, and build a complete mechanism of investment process and
are not affected by market sentiment about the strict principles of
investment. "Qi" is to encourage the formation of reverse thinking,
each new investment strategy is always the first to understand the
different income and traditional market driving factors and
endogenous risk.
Invest in change
In the eyes of Zhang Lei, the essence of Hillhouse capital "is
an investment company to change". In this era, emerge in an endless
stream of innovation, change is the only eternal, everlasting
enterprise always worth the investment, capital's mission is to
help those who dare to embrace change entrepreneurial dreams. These
entrepreneurs can constantly adjust their response according to the
change, "moat".
Zhang Lei thinks, good company on the Internet when the tide, to
dig their "moat", take the initiative to embrace the Internet
brings change. From this perspective, the type of government to
protect the "moat" is very fragile, at any time may collapse. The
real moat is long-term to create the greatest value, to create
maximum value and use the most efficient way and lowest cost.
Entrepreneurs every morning, should I ask myself, where is the
moat, his day's work, is on the increase in the consumption of the
moat, or moat.
"I think it must be at risk, if he feels that risk is a price,
or people will look at him on the board, he will not dare to risk.
So, entrepreneurs, the biggest risk is unchanged, he not to risk is
the biggest risk in shareholders. So, all we do is let him go he
should take the risk, which is why we go to the design and control
of the company to make the founders. You know what the final
whatever you decide, I will support you, this is our philosophy."
Zhang Lei . In order to let entrepreneurs have no worries to
embrace change, insist on Hillhouse capital through the design of
control, allows the company to do the company's control of their
Tencent Jingdong is a strategic investment, the two companies in
the face of change and make decisions. At that time, Tencent's fast
and easy in the fierce competition in the electricity supplier
giant scissors Jingdong, although now business second spot, but
still a large gap between the face of ali. As the two companies
together investors, Zhang Lei played a matchmaking role in Tencent
and Jingdong in marriage. He said to Ma Huateng, all things Tencent
are selling virtual goods business, business platform easy fast,
but should face a never experienced word - "inventory", business is
bigger, more inventory. For Liu Qiangdong, Zhang Lei will focus on
the mobile trend, Jingdong PC terminal sales network is very good,
but also the establishment of logistics warehousing system
complete, but the lack of mobile gene.
With "inventory" and "mobile" two words, Jingdong and Tencent
these two companies seem to be lack of similarity to sit together.
Tencent shares Jingdong, can expand its influence in the field of
physical electricity supplier at the same time, the company can
better develop the e-commerce service ecology, such as pay, public
accounts and the effect of advertising platform, create a more
prosperous ecosystem services for all electricity suppliers on its
platform. You can get Jingdong entrance WeChat and mobile phone QQ,
to come into contact with Tencent huge mobile social crowd.
For investors, the marriage of Jingdong and Tencent effect is
more obvious. By the end of 2013 Jingdong valuation of only
$, in 2014 March Tencent shares, Jingdong valuation
reached $. In May Jingdong listing, the market value is
Jingdong soared to $. To April 17, 2015 closing price
calculation, the market value has risen to $ Jingdong.
In the Jingdong value rising, whether it is the top two
shareholders of Tencent and Liu Qiangdong, still ranked third in
fourthHillhouse capital and other investors, the hand chip
corresponding to the value of rapid growth.
The marriage of Jingdong and Tencent, can the integration of
industrial chain, mutual exchange of needed products to create new
value. Different drops and fast merge logic and. In a taxi software
war, consumer habits have been gradually cultivated, it is
difficult to create new value to continue to burn. Zhang Lei
thinks, the merger of the two companies, can burn less money,
thereby putting money back into better, differentiated
Under the leadership of Zhang Lei, Hillhouse capital since the
establishment of the impressive performance. The British "Financial
Times" reported that in 2012, Hillhouse capital since its
inception, the average annual compound rate of return of up to 52%,
even in 2008 there have been 37% decline. In 2015, New York Shibao
Chinese network quoted one investor said, Hillhouse capital since
the establishment of the average annual rate of return of 39%.
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